

CellAction
Cell Therapy Acceleration and Innovation
Heads:
1. Dr. Marion Alcantara; 2. Dr. Sebastian Amigorena
Objectives
• Offering a collaborative platform that engages partners at every stage: research, preclinical and translational.
• Bridging the gap from scientific concept to product development.
• Developing GMP-ready products.
• Understanding modes and mechanisms.
Operator (s)
Technology and expertises
Pre-GMP cell & gene therapy development
• Highly qualified technical and scientific team
• Integrated clinical expertise
• Pre-GMP environment
In vitro and in vivo PoC analyses
Facilities and activities
Pre-GMP CAR-T cell engineering and manufacturing
Technology highlights: CliniMACS Prodigy platform / GMP-compliant electroporatorsAnalytical development
Technology highlights: MACSQuant cytometer / digital PCR (Nio(r))In vitro PoC
Technology highlights: Lumicks z-Movi cell avidity analyzer, xCELLigence RTCA eSight real-time live cell analyser, spectral flow cytometry platform, single-cell omics (10X Genomics), Jess automated Western blot (Bio-Techne)In vivo PoC
Technology highlights: Xenograft and syngeneic tumor models, imaging (bioluminescence, fluorescence), stereotaxic neurosurgery, ex vivo analyses (flow cytometry, IHC, IF)
CellAction from the Institut Curie brings expertise and cutting-edge technologies
to provide a complete solution for GMP-compliant cell engineering and scalable
manufacturing for clinical testing, bringing a new momentum for innovative clinical trials.


